Neurophysiological effects of flavoring and caffeine-added toothpaste

Abstract

In this study, the neurophysiological effects of toothpaste containing flavoring and caffeine were examined to enhance the fatigue-reducing effect of toothbrushing. The research focused on the impact of these ingredients on flicker values, event-related potentials P300, and mood scales. Results showed that toothpaste with flavoring and caffeine significantly shortened the P300 peak latency, suggesting its potential for reducing fatigue. The study aimed to clarify how these components could enhance brain information processing ability and suppress the decline in processing due to mental fatigue.

Subjects and Methods

The study involved 13 healthy adults who performed a 25-minute calculation task before and after brushing their teeth with the respective toothpaste. The incorporation of caffeine was expected to enhance the fatigue-reducing effect of active rest, and trials were conducted to evaluate the impact of flavor components and caffeine on the brain's information processing ability.

Toothpaste Formulations and Experimental Procedure

The dentifrice used in the experiment contained flavoring ingredients and anhydrous caffeine, while the control formulation did not. Subjects underwent an auditory oddball task to assess information processing ability. ERP waveforms were obtained and analyzed to understand the effects of the toothpaste components on brain activity.

Manabu Hosoya, Yoshinori Murakami, Hidetoshi Sadatsu and Yukihiro Yoda - Neurophysiological effects of flavoring and caffeine-added toothpaste - Flipbook by Fleepit