Promising Influences of Caffeic Acid and Caffeic Acid Phenethyl Ester Against Toxins

Introduction

Toxins can be harmful substances classified as natural or chemical toxins, causing various types of injuries through mechanisms like inflammation, oxidative stress, apoptosis, and necrosis.

Caffeic Acid and CAPE Pharmacokinetics and Activities

Caffeic acid and CAPE are natural compounds with antioxidant and anti-inflammatory properties found in various plants. They have potential therapeutic applications and protective effects against natural and chemical toxins.

Safety Evaluation

Despite their anti-cancer properties, caffeic acid phenethyl ester and caffeic acid do not exhibit adverse effects on normal cells. Studies are ongoing to explore their toxic and safety effects further.

Findings and Discussion

Chemical Toxins

Studies have demonstrated the protective effects of caffeic acid and CAPE against various chemical toxins, including heavy metals like cadmium, chromium, and aluminum, as well as substances like carbon tetrachloride and 1-methyl-4-phenylpyridinium.

Natural Toxins

Research has shown the potential of caffeic acid and CAPE in mitigating the effects of natural toxins such as amyloid beta, Candida albicans, Staphylococcus, and Streptococcus. These compounds exhibit antimicrobial, antifungal, and anti-inflammatory properties.

Organ Effects

Caffeic acid and CAPE have demonstrated protective effects on various organs affected by toxins, including the liver, kidneys, brain, and heart. They show promise in reducing toxicity-induced damage and improving organ function.

Basiru O. Ajiboye, Mehdi Alizadeh, Vahid Reza Askari, Sajjad Ehtiati, Faeghe Farhadi, Kimia Khalatbari and Vafa Baradaran Rahimi - Promising influences of caffeic acid and caffeic acid phenethyl ester against natural and chemical toxins - Flipbook by Fleepit